New strategies for cardiac repair using polymer-based drug delivery systems loaded with growth factors

  1. Pascual Gil de Gómez, Simón
Zuzendaria:
  1. María José Blanco Prieto Zuzendaria
  2. Felipe Prósper Cardoso Zuzendarikidea

Defentsa unibertsitatea: Universidad de Navarra

Fecha de defensa: 2018(e)ko ekaina-(a)k 25

Epaimahaia:
  1. José Antonio Páramo Fernández Presidentea
  2. Josune Orbe Idazkaria
  3. Ana Colette Pereira de Castro Osorio Mauricio Kidea
  4. Gorka Orive Arroyo Kidea
  5. Mariana Landín Pérez Kidea

Mota: Tesia

Teseo: 146906 DIALNET lock_openDadun editor

Laburpena

Myocardial infarction (MI) is the main cardiovascular disease, causing more than 7 million deaths per year 1. In spite of its clinical relevance 2,3, this pathology is from been controlled and risk factors associated to it are considerably augmenting in modern society, as pointed out by the World Health Organization, which has estimated that the number of MI events will dramatically increase by 2030 1. MI is usually started by the occlusion of a coronary artery, that causes an ischemic condition in the cardiac tissue. This lack of oxygen supply induces a massive cell death of cardiac cells and a negative tissue remodeling takes place. Consequently, functional limitations and eventually death may occur.