Prevalence of plasma lipid abnormalities and its association with glucose metabolism in SpainThe di@bet.es study
- Martínez Hervás, Sergio
- Carmena Rodríguez, Rafael
- Ascaso Gimilio, Juan Francisco
- Real Collado, José Tomás
- Masana Marín, Lluís
- Catalá Bauset, Miguel
- Vendrell Ortega, Joan
- Vázquez, José Antonio
- Valdés Hernández, Sergio
- Urrutia, Inés
- Soriguer Escofet, Federico
- Serrano Ríos, Manuel
- Rojo Martínez, Gemma
- Ortega, Emilio
- Mora Peces, Inmaculada
- Menéndez Torre, Edelmiro
- Martínez Larrad, María Teresa
- López Alba, Alfonso
- Gomis, Ramón
- Goday Arno, Alberto
- Girbés Borrás, Juan
- Gaztambide Saenz, Sonia
- Franch Nadal, Josep
- Delgado Álvarez, Elías
- Castell Abat, Conxa
- Castaño González, Luis
- Casamitjana, Roser
- Calle Pascual, Alfonso Luis
- Bordiú, Elena
- Show all authors +
ISSN: 0214-9168, 1578-1879
Year of publication: 2014
Volume: 26
Issue: 3
Pages: 107-114
Type: Article
More publications in: Clínica e investigación en arteriosclerosis
Abstract
Introduction: Dyslipidemia is a significant contributor to the elevated CVD risk observed in type 2 diabetes mellitus. We assessed the prevalence of dyslipidemia and its association with glucose metabolism status in a representative sample of the adult population in Spain and the percentage of subjects at guideline-recommended LDL-C goals. Material and methods: The di@bet.es study is a national, cross-sectional population-based survey of 5728 adults. Results: A total of 4776 subjects were studied. Dyslipidemia was diagnosed in 56.8% of subjects; only 13.2% of subjects were treated with lipid lowering drugs. Lipid abnormalities were found in 56.8% of Spanish adults: 23.3% with high LDL-C, 21.5% high TG, 35.8% high non-HDL-C, and 17.2% low HDL-C. Most normal subjects showed an LDL-C = 3.36 mmol/l. Pre-diabetics presented similar proportion when considering a goal of 3.36 mmol/l, but only 35% of them reached an LDL-C goal = 2.6 mmol/l. Finally, 45.3% of diabetics had an LDL-C = 2.6 mmol/l, and only 11.3% achieved an LDL-C = 1.8 mmol/l. Conclusions: Our study demonstrates a high prevalence of dyslipidemia in the adult Spanish population, and a low use of lipid-lowering drugs. Moreover, the number of subjects achieving their corresponding LDL-C goal is small, particularly in subjects at high cardiovascular risk, such as diabetics.