Atzoko baliabideak, biharko osasunaardo-hondakinak eta kannabisa
- Oier Aizpurua-Olaizola
- Patricia Navarro
- Nestor Etxebarria
- Aresatz Usobiaga
ISSN: 0214-9001
Year of publication: 2018
Issue Title: 2015-2016 Euskal Tesien 15 pasarte
Issue: 1
Pages: 77-88
Type: Article
More publications in: Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria
Abstract
This thesis was divided in two lines of research. On the one hand, supercrit-ical fluid extraction was successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes. Unfortunately, polyphenols have poor long-term stability and poor bioavailability, so they were microencapsulated. On the other hand, 3 different studies were done around medical use of cannabis. Firstly, in order to corre-late plants with their physiological effects, an analysis method was developed to estab-lish the cannabinoid fingerprinting of different cannabis plants. A method for the quan-tification of major cannabinoids and their metabolites in human urine and plasma was also developed. Finally, in order to optimize the production of bioactive compounds, the evolution of cannabinoid and terpene content of different chemotype plants during their growth was studied.