Cirrosis alcohólica y osteodistrofia hepática¿cuáles son los principales factores implicados?
- Escalante, M.
- Franco, R.
- Cubas, L.
- Goiría, J.I.
- Zulueta, M.L.
- Cabarcos, A.
- Duque, C.
- Miguel, F.
ISSN: 0304-4858, 2173-2302
Datum der Publikation: 2003
Ausgabe: 100
Nummer: 2
Seiten: 47-49
Art: Artikel
Andere Publikationen in: Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios
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Zusammenfassung
OBJECTIVES: To know the prevalence of bone disease in alcoholic cirrhotic males from 45 to 65 years old. To prove the intervention of several factors usually involved in hepatic osteodystrophy.SUBJECTS AND METHODS: study population: 52 alcoholic cirrhotic males from 45 to 65 years old. Design and variables: transversal descriptive study. The following factors were evaluated: bone disease: thoracic and lumbar spine standard X-ray and bone densitometry (dual energy X-ray absorptimetry-DPX plus LUNAR-DEXA) were performed), nutritional state: anthropometric evaluation (measuring skin thickness) and total body densitometry, factors usually involved in hepatic osteodystrophy: active alcoholism, smoking, diabetes, hypogonadism and physical execise and clinical severity of cirrhosis: Child-Turcotte classification.Statistical analysis: Macintosh computer (program Filemaker PRO).RESULTS: 58% of patients had loss of bone mass. 80,85% were Child A, 12,76% Child B and 6,39% Child C. Bone disease was present in 52,63% of Child A, 83,33% of Child B and 100% of Child C.DISCUSSION AND CONCLUSIONS: the prevalence of osteopenia was higher than in other studies. The usual risk factors were no relevant in losing bone mass except for smoking. The clinical severity of cirrhosis was significantly related to the loss of bone mass in these patients.