Expresión de Proteínas Relacionadas con Resistencia a Múltiples Drogas (MDR-Proteínas) en tumores sólidos
- Paredes-Lario, A.
- Blanco-García, J.L.
- Echenique-Elizondo, M.
ISSN: 0304-4858, 2173-2302
Year of publication: 2006
Volume: 103
Issue: 4
Pages: 163-175
Type: Article
More publications in: Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios
Abstract
Research lines on cancer are oppressing in number. Many of them are based on the search of new treatment approaches. Other,not less important, try to ascertain the reason, as opposed to enough heamathological neoplasm as leukemias and lymphomas,the majority of solid tumors, cannot be cured with chemotherapy. Without doubt, the causes that a tumoral cell can be resistantto chemotherapy are many and of various nature. The motive of the present work is that of carrying out a review and update ofone of these possible causes, in concrete, that of the expresion of proteins related to the resistance to multiple drugs –MDRproteins.