Neumonía intersticial no específica (NINE) secundaria al tratamiento con imatinib. A propósito de un caso y revisión de la literatura
- Azofra-Macarrón, Carlos 1
- Robaina-Cabrera, Dimas Manuel 1
- Anta-Fernández, Manuela 2
- González-Pascual, Andrea 2
- Miguel-Sánchez, Carlos de 3
- 1 Servicio de Medicina Familiar y Comunitaria, Hospital Sierrallana, Torrelavega (Cantabria), España
- 2 Servicio de Medicina Interna, Hospital Sierrallana, Torrelavega (Cantabria), España
- 3 Servicio de Hematología, Hospital Sierrallana, Torrelavega (Cantabria), España
ISSN: 2530-0792
Year of publication: 2017
Issue Title: Spanish Journal of Case Records in Internal Medicine
Volume: 2
Issue: 3
Pages: 128-130
Type: Article
More publications in: Revista Española de Casos Clínicos en Medicina Interna (RECCMI)
Abstract
Imatinib is a powerful and selective inhibitor of the protein tirosine kinase BCR-ABL with clinical significant efficacy for the treatment of chronic myeloid leukemia (CML). Pulmonary toxicity induced by Imatinib has got a wide range of presentations and symptoms, being the interstitial neumonitis an exceptional example regarding literature. In this case, patients normally show a non specific interstitial neumonitis and evolution is generally good after treatment withdrawal and therapy with esteroids. We present the case of a 74-years-old male with interstitial neumonitis caused by Imatinib prescribed for CML in chronic phase.
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