Síndrome de DRESS en un paciente tratado con sulfasalazina y amoxicilina-ácido clavulánico

  1. Nogueiras-Álvarez, Rita 1
  2. Gutiérrez-González, Aurora 2
  3. Montenegro-Echeverría, Estefanía Alejandra 3
  4. Arnáiz-García, Ana María 4
  1. 1 Servicio de Farmacología Clínica. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España
  2. 2 Servicio de Alergología. Hospital El Bierzo. Ponferrada. León. España
  3. 3 Servicio de Alergología. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España
  4. 4 Servicio de Medicina Interna. Hospital Universitario Marqués de Valdecilla. Santander. Cantabria. España
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Journal:
Revista Española de Casos Clínicos en Medicina Interna (RECCMI)

ISSN: 2530-0792

Year of publication: 2020

Issue Title: Spanish Journal of Case Records in Internal Medicine

Volume: 5

Issue: 3

Pages: 129-132

Type: Article

DOI: 10.32818/RECCMI.A5N3A11 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Revista Española de Casos Clínicos en Medicina Interna (RECCMI)

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Abstract

DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a drug-induced hypersensitivity syndrome that occurs between 2-6 weeks after the first taking of the responsible drug. We describe the case of a 57-year-old man who was admitted to our hospital due to a respiratory infection and a skin rash that was placed in the context of a DRESS syndrome. The cutaneous manifestations worsened after the intake of amoxicillin during concomitant treatment with sulfasalazine. When DRESS syndrome is suspected, withdrawal of the responsible drugs is crucial to avoid a possible fatal outcome.

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