Protocolo diagnóstico de la trombofilia

  1. Sierra Aisa, C.
  2. Moretó Quintana, A.
  3. Iruín Irulegui, G.
  4. Martín Martitegui, X.
  5. García-Ruiz, J.C.
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Series: 12

Issue: 22

Pages: 1299-1303

Type: Article

DOI: 10.1016/J.MED.2016.10.024 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Sustainable development goals

Abstract

Abstract Introduction Thrombophilias are hereditary or acquired conditions which can increase the risk of venous or arterial thrombosis. Aetiology It can be a multifactorial disorder where congenital defects of anticoagulant or procoagulant factors may be combined with acquired hematological abnormalities. Diagnosis The study of these alterations, should be considered in patients with a documented unexplained thrombotic episode or a positive family history.

Bibliographic References

  • Merriman l, Greaves M. Testing for thrombophilia: an evidence-based approach. Postgrad Med J. 2006;82:699-704.
  • Rosendaal Fr, Reitsma PH. Genetics of venous thrombosis. J Thromb Haemost. 2009:7Suppl1:301-4.
  • Heit JA. The epidemiology of venous thromboembolism in the commu-nity. Arterioscler Thromb Vasc Biol. 2008;28:370-2.
  • Moll S. Thrombophilia: clinical-practical aspects. Thromb Thromboly-sis. 2015;39(3):367-78.
  • Stevens SM, Woller SC, Bauer KA, Kasthuri R, Cushman M, Streiff M, et al. Guidance for the evaluation and treatment of here-ditary and acquired thrombophilia. J Thromb Thrombolysis. 2016; 41(1):154-64.
  • Pastori D, Parrotto S, Vicario T, Saliola M, Mezzaroma I, Violi F, et al. Antiphospholipid syndrome and anticoagulation quality: a clinical cha-llenge. Atherosclerosis. 2016;244:48-50.
  • Cohn DM, Vansenne F, Kaptein AA, De Borgie CA, Middeldorp S. The psychological impact of testing for thrombophilia: a systematic review. J Thromb Haemost. 2008;6:1099-104.