Distonía tardía asociada a olanzapina

  1. J.J. López 1
  2. P. Moreno 1
  3. M. Prieto 1
  4. M.D. Gea 1
  1. 1 Hospital de Baza
    info

    Hospital de Baza

    Baza, España

Revista:
Psiquiatría biológica: Publicación oficial de la Sociedad Española de Psiquiatría Biológica

ISSN: 1134-5934

Año de publicación: 2001

Volumen: 8

Número: 5

Páginas: 207-207

Tipo: Artículo

Otras publicaciones en: Psiquiatría biológica: Publicación oficial de la Sociedad Española de Psiquiatría Biológica

Resumen

Tardive dystonia is a drug-induced movement disorder characterized by sustained involuntary muscle constractions or other postural abnormalities. This disorder is secondary to the use of any type of medication blocking the dopamine receptor. Olanzapine is an atypical antipsychotic associated with a low risk of presenting extrapyramidal side effects. We present a case of a 19-year-old patient with a schizoaffective disorder who initiated olanzapine treatment (20 mg/d). After 18 months of treatment the patient developed tardive dystonia. Treatment with clozapine and botulinic toxin were administered with good response. Conclusion: Movement disorders should be carefully evaluated in patients with affective psychosis/schizoaffective disorders undergoing treatment with olanzapine.