Alterazio kromosomikoak dituzten espermatozoideak identifikatzeko biomarkatzaileen hautaketa
- Ainize Odriozola Larrañaga
- Itziar Urizar Arenaza
- Beatriz Navarro Santos
- Irune Calzado López
- Malen Zabala Goikoetxea
- Nerea Subiran Ciudad
- Olatz Arbelaitz Gallego (ed. lit.)
- Ainhoa Latatu (ed. lit.)
- Elixabete Pérez Gaztelu (ed. lit.)
Publisher: Udako Euskal Unibertsitatea, UEU = Universidad Vasca de Verano
ISBN: 978-84-8438-862-3, 978-84-8438-866-1
Year of publication: 2023
Pages: 139-144
Congress: Ikergazte. Nazioarteko Ikerketa Euskaraz (5. 2023. Donostia)
Type: Conference paper
Abstract
Infertile men with a normal genetic supply (normal karyotype) may have chromosomal alterations in their sperm cells. The most frequent chromosomal alterations are aneuploidies, which are detected by FISH study, but this analysis involves the destruction of the sample. Moreover, after diagnosis, there is no alternative treatment for these patients and the main option to the man and the couple is to replace the male gamete with a sperm donor. This study aims to create novel tools to identify sperm cells with aneuploidies using proteomic techniques.