Enfermedad de Devic

Résumé

Introduction: Devic’s disease, also known as neuromyelitis optica, is an idiopathic, demyelinating, autoimmune disorder of the central nervous system1-5. It is characterised by predominantly affecting the optic nerve and spinal cord through inflammatory lesions6. Objective: to provide a clinical update on the epidemiology, diagnosis, pathophysiology and treatment of Devic syndrome. Methods: a review was carried out in databases such as Web Of Science, Embase, PubMed and PEDro. Results: various studies show great heterogeneity in determining its prevalence and incidence7,8. The differential diagnosis with respect to other clinical entities such as multiple sclerosis, with which it seemed to be associated in the past, is made by humoral antibody detection, which seems to be the most sensitive and valid method for this purpose1,3. On the other hand, as far as treatment is concerned, there is still no cure, nor is there a clear approach to avoid possible relapses1,6.