Additional file 7 of Sex bias in celiac disease: XWAS and monocyte eQTLs in women identify TMEM187 as a functional candidate gene

  1. Hernangomez-Laderas, Alba 1
  2. Cilleros-Portet, Ariadna 1
  3. Martínez Velasco, Silvia
  4. Marí, Sergi 1
  5. Legarda, María
  6. González-García, Bárbara Paola 1
  7. Tutau, Carlos
  8. García-Santisteban, Iraia 1
  9. Irastorza, Iñaki
  10. Fernandez-Jimenez, Nora 1
  11. Bilbao, Jose Ramon 12
  1. 1 Universidad del País Vasco/Euskal Herriko Unibertsitatea
    info

    Universidad del País Vasco/Euskal Herriko Unibertsitatea

    Lejona, España

    ROR https://ror.org/000xsnr85

  2. 2 Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas

Editor: figshare

Año de publicación: 2024

Tipo: Dataset

CC BY 4.0

DOI: 10.6084/M9.FIGSHARE.26651772 lock_openAcceso abierto editor

Resumen

Additional file 7. cis-eQTLs identified in the X chromosome by cis-eQTL analysis of LPS-stimulated female monocytes at nominal P-value < 5 × 10–8. A total of 150 cis-eQTLs, implicating 94 SNPs, 9 probes and 8 genes were identified on the X chromosome of LPS-stimulated female monocytes. n_var_in_cis: the total number of variants tested in cis; dist_gene_var: the distance between the gene and the tested variant; var_position: the position of the variant; nom_pval: the nominal P-value of the association between the variant and the gene; r_squared: the correlation coefficient of the linear regression; slope: the slope (beta) of the linear regression; slope_se: the standard error of the beta.

Referencias bibliográficas

  • 10.1038/s41572-018-0054-z
  • 10.1016/j.cgh.2017.06.037
  • 10.1016/j.cgh.2018.11.013
  • 10.1016/s0198-8859(03)00027-2
  • 10.1038/ng.543
  • 10.1038/ng.998
  • 10.1038/ejhg.2016.120
  • 10.1016/j.ajhg.2018.04.002
  • 10.1038/ng.3268
  • 10.1371/journal.pone.0113684
  • 10.1038/nm.3933
  • 10.1016/j.ajhg.2013.03.017
  • 10.3389/fendo.2019.00511
  • 10.1016/j.clim.2016.04.002
  • 10.1002/art.39560
  • 10.1002/art.23701
  • 10.1038/nri2394
  • 10.1016/j.jaut.2011.11.012
  • 10.1146/annurev.immunol.26.021607.090326
  • 10.1007/s10875-006-9061-z
  • 10.1016/j.febslet.2004.06.057
  • 10.1126/science.1246949
  • 10.1038/ng.3538
  • 10.1093/hmg/ddz113
  • 10.3389/fgene.2020.562434
  • 10.1086/519795
  • 10.1038/ng.3656
  • 10.1038/ng2088
  • 10.1002/gepi.20310
  • 10.21105/joss.00731
  • 10.1016/j.ajhg.2010.11.011
  • 10.1038/srep32894
  • 10.1038/ncomms15452
  • 10.1016/j.cell.2018.10.022
  • 10.1136/annrheumdis-2012-202742
  • 10.1136/annrheumdis-2012-201851
  • 10.1002/art.37804
  • 10.1007/s12017-017-8443-0
  • 10.1038/nature15393
  • 10.1371/journal.pone.0146276
  • 10.1155/2017/4915950
  • 10.1371/journal.pone.0197915
  • 10.1371/journal.pgen.1005908
  • 10.1016/s0140-6736(23)00457-9