Breast cancer cell-derived extracellular vesicles accelerate collagen fibrillogenesis and integrate into the matrix

  1. Tam, Nicky Wai-Kay 1
  2. Dimova, Rumiana 1
  3. Cipitria, Prof. Amaia 123
  1. 1 Max Planck Institute of Colloids and Interfaces
    info

    Max Planck Institute of Colloids and Interfaces

    Potsdam, Alemania

    ROR https://ror.org/00pwgnh47

  2. 2 Instituto de Investigación Sanitaria Biogipuzkoa
    info

    Instituto de Investigación Sanitaria Biogipuzkoa

    San Sebastián, España

    ROR 01a2wsa50

  3. 3 Ikerbasque
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Editor: Edmond

Year of publication: 2024

Type: Dataset

DOI: 10.17617/3.AMI3GV lock_openOpen access editor

Abstract

Rheometry of collagen I hydrogels formed in the presence of extracellular vesicles, extruded plasma membrane vesicles, and synthetic liposomes; combined confocal reflectance imaging of collagen I fibrils and fluorescence confocal imaging of labelled vesicles, with processed data and analysis of collagen fibril length, matrix mesh size, and particle-fibril co-localization