TRASTORNOS CONGÉNITOS DEL METABOLISMO
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublicaciones en colaboración con investigadores/as de Ikerbasque, Fundación Vasca para la Ciencia (26)
2024
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Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Cell Reports Medicine, Vol. 5, Núm. 7
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Spatial metabolomics and its application in the liver
Hepatology, Vol. 79, Núm. 5, pp. 1158-1179
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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis
Metabolism: Clinical and Experimental, Vol. 158
2023
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Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, Vol. 77, Núm. 5, pp. 1654-1669
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
2022
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Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH)
Gastroenterologia y Hepatologia, Vol. 45, Núm. 9, pp. 724-734
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Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen
Antioxidants, Vol. 11, Núm. 5
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Hepatology, Vol. 75, Núm. 3, pp. 550-566
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Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients
Cell Death Discovery, Vol. 8, Núm. 1
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Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage
Nature Communications, Vol. 13, Núm. 1
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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes
Communications Biology, Vol. 5, Núm. 1
2021
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Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
Cell Death and Disease, Vol. 12, Núm. 6
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Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
JHEP Reports, Vol. 3, Núm. 3
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
Molecular Genetics and Metabolism Reports, Vol. 26
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
2020
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Brain circuit alterations and cognitive disability in late-onset cobalamin d disorder
Journal of Clinical Medicine, Vol. 9, Núm. 4
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Multi‐omics integration highlights the role of ubiquitination in ccl4‐induced liver fibrosis
International Journal of Molecular Sciences, Vol. 21, Núm. 23, pp. 1-19
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Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation
Nature Communications, Vol. 11, Núm. 1