Publications by the researcher in collaboration with Asier Benito Vicente (44)

2024

  1. OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues

    Advanced Science, Vol. 11, Núm. 13

2023

  1. Age, Origin and Functional Study of the Prevalent LDLR Mutation Causing Familial Hypercholesterolaemia in Gran Canaria

    International Journal of Molecular Sciences, Vol. 24, Núm. 14

  2. Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia: From Molecular Mechanisms Causing Pathogenicity to New Therapeutic Approaches

    International Journal of Molecular Sciences

  3. Functional Characterization of p.(Arg160Gln) PCSK9 Variant Accidentally Found in a Hypercholesterolemic Subject

    International Journal of Molecular Sciences, Vol. 24, Núm. 4

  4. Predictive Modeling and Structure Analysis of Genetic Variants in Familial Hypercholesterolemia: Implications for Diagnosis and Protein Interaction Studies

    Current Atherosclerosis Reports, Vol. 25, Núm. 11, pp. 839-859

2022

  1. Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model

    Small, Vol. 18, Núm. 13

  2. Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids

    Hepatology, Vol. 76, Núm. 6, pp. 1617-1633

  3. Familial hypercholesterolemia

    Cholesterol: From Chemistry and Biophysics to the Clinic (Elsevier), pp. 501-524

  4. Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant Hypercholesterolemia

    Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 42, Núm. 7, pp. E203-E216

  5. Pathophysiology of Atherosclerosis

    International Journal of Molecular Sciences, Vol. 23, Núm. 6

  6. Towards a new generation of non-cytotoxic shape memory thermoplastic polyurethanes for biomedical applications

    Materials Today Communications, Vol. 33

2021

  1. (r)HDL in theranostics: How do we apply HDL's biology for precision medicine in atherosclerosis management?

    Biomaterials Science, Vol. 9, Núm. 9, pp. 3185-3208

  2. A systematic approach to assess the activity and classification of pcsk9 variants

    International Journal of Molecular Sciences, Vol. 22, Núm. 24

  3. Kukutxeztula: «gainditutako» gaitz baten itzulera

    Ekaia: Euskal Herriko Unibertsitateko zientzi eta teknologi aldizkaria, Núm. 39, pp. 61-78

  4. LDLR variants functional characterization: Contribution to variant classification

    Atherosclerosis, Vol. 329, pp. 14-21

  5. MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants

    JACC: Basic to Translational Science, Vol. 6, Núm. 11, pp. 815-827

  6. Molecular mechanisms of lipotoxicity-induced pancreatic β-cell dysfunction

    International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 357-402

  7. Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town

    Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 41, Núm. 2, pp. 934-943

2020

  1. Cholesterol efflux efficiency of reconstituted HDL is affected by nanoparticle lipid composition

    Biomedicines, Vol. 8, Núm. 10

  2. Hiperkolesterolemia Familiarra: patofisiologia, diagnostikoa eta tratamendua

    Osagaiz: osasun-zientzien aldizkaria, Vol. 4, Núm. 1, pp. 69-80