STRUCTURAL GLYCOIMMUNOLOGY
Ikerbasque, Fundación Vasca para la Ciencia
Bilbao, EspañaPublications in collaboration with researchers from Ikerbasque, Fundación Vasca para la Ciencia (17)
2024
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Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate
Nature Communications, Vol. 15, Núm. 1
2023
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Modulating antibody effector functions by Fc glycoengineering
Biotechnology Advances, Vol. 67
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SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression
Nucleic Acids Research, Vol. 51, Núm. 1, pp. 144-165
2022
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Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE
Nature Communications, Vol. 13, Núm. 1
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Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases
Current Opinion in Structural Biology, Vol. 72, pp. 248-259
2021
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GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
Journal of Biological Chemistry, Vol. 297, Núm. 2
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Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA
Science Advances, Vol. 7, Núm. 42
2020
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Dissecting the Structural and Chemical Determinants of the "open-To-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria
Biochemistry, Vol. 59, Núm. 32, pp. 2934-2945
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Membrane fluidity adjusts the insertion of the transacylase PlsX to regulate phospholipid biosynthesis in Gram-positive bacteria
Journal of Biological Chemistry, Vol. 295, Núm. 7, pp. 2136-2147
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Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
Nature Communications, Vol. 11, Núm. 1
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Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila
Nature Communications, Vol. 11, Núm. 1
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Structural insights into the mechanisms and specificities of IgG-active endoglycosidases
Glycobiology, Vol. 30, Núm. 4, pp. 268-279
2019
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Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
ACS Central Science, Vol. 5, Núm. 3, pp. 524-538
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Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases
Methods in Enzymology (Academic Press Inc.), pp. 261-279
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Structural basis of glycogen metabolism in bacteria
Biochemical Journal, Vol. 476, Núm. 14, pp. 2059-2092
2018
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Structural basis for the recognition of complex-Type N-glycans by Endoglycosidase S
Nature Communications, Vol. 9, Núm. 1
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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria
ACS Chemical Biology, Vol. 13, Núm. 1, pp. 131-140