Publicaciones en colaboración con investigadores/as de University of Toronto (17)

2023

  1. A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo

    Science translational medicine, Vol. 15, Núm. 697, pp. eadf4549

  2. Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

    Cell Reports, Vol. 42, Núm. 4

2022

  1. Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells

    Antimicrobial Agents and Chemotherapy, Vol. 66, Núm. 7

  2. Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 4

2021

  1. Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

    iScience, Vol. 24, Núm. 9

  2. Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

    Science Advances, Vol. 7, Núm. 49

  3. Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

    Scientific Reports, Vol. 11, Núm. 1

  4. Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

    Nature Communications, Vol. 12, Núm. 1

2020

  1. Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments

    Cell Reports, Vol. 32, Núm. 7

  2. Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

    Nature Communications, Vol. 10, Núm. 1

2014

  1. Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: Implications for antibody recognition mechanism and immunogen design

    Journal of Biological Chemistry, Vol. 289, Núm. 10, pp. 6565-6580

2008

  1. Cationic lipids as gene transfer agents: A patent review

    Expert Opinion on Therapeutic Patents, Vol. 18, Núm. 5, pp. 515-524

2006

  1. Use of DNA microarray technology and gene expression profiles to investigate the pathogenesis, cell biology, antifungal susceptibility and diagnosis of Candida albicans

    FEMS Yeast Research

2001

  1. Influence of hepatic regeneration after partial hepatectomy on theophylline pharmacokinetics in rats

    European Journal of Drug Metabolism and Pharmacokinetics, Vol. 26, Núm. 1-2, pp. 53-58

1997

  1. Influence of partial hepatectomy in rats on the activity of hepatic microsomal enzymatic systems

    European Journal of Drug Metabolism and Pharmacokinetics, Vol. 22, Núm. 1, pp. 15-23

  2. Influence of route of administration and dosage form in the pharmacokinetic and bioavailability of salbutamol

    European Journal of Drug Metabolism and Pharmacokinetics, Vol. 22, Núm. 2, pp. 145-150