EDURNE
RUJAS DÍEZ
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University of Toronto
Toronto, CanadáPublicaciones en colaboración con investigadores/as de University of Toronto (12)
2023
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A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo
Science translational medicine, Vol. 15, Núm. 697, pp. eadf4549
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Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
Cell Reports, Vol. 42, Núm. 4
2022
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Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells
Antimicrobial Agents and Chemotherapy, Vol. 66, Núm. 7
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Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Núm. 4
2021
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Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
iScience, Vol. 24, Núm. 9
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Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
Science Advances, Vol. 7, Núm. 49
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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease
Scientific Reports, Vol. 11, Núm. 1
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Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers
Nature Communications, Vol. 12, Núm. 1
2020
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Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments
Cell Reports, Vol. 32, Núm. 7
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Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies
Nature Communications, Vol. 11, Núm. 1
2019
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Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
Nature Communications, Vol. 10, Núm. 1
2014
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Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: Implications for antibody recognition mechanism and immunogen design
Journal of Biological Chemistry, Vol. 289, Núm. 10, pp. 6565-6580