Publications en collaboration avec des chercheurs de Instituto de Química Médica (12)

2024

  1. The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls

    EMBO Molecular Medicine, Vol. 16, Núm. 4, pp. 755-783

2018

  1. Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria

    Science Translational Medicine, Vol. 10, Núm. 459

2014

  1. Combining rimonabant and fentanyl in a single entity: Preparation and pharmacological results

    Drug Design, Development and Therapy, Vol. 8, pp. 263-277

2013

  1. Description of a bivalent cannabinoid ligand with hypophagic properties

    Archiv der Pharmazie, Vol. 346, Núm. 3, pp. 171-179

2010

  1. Synthesis and pharmacological evaluation of new (E)- and (Z)-3-aryl-4-styryl-1H-pyrazoles as potential cannabinoid ligands

    Arkivoc, Vol. 2010, Núm. 10, pp. 226-247

2007

  1. Synthesis and pharmacological evaluation of chlorinated N-alkyl-3- and -5-(2-hydroxyphenyl)pyrazoles as CB 1 cannabinoid ligands

    Monatshefte fur Chemie, Vol. 138, Núm. 8, pp. 797-811

2006

  1. Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the μ-opioid receptor and I2-imidazoline binding sites

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 19, pp. 6570-6580

2004

  1. Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: A new series of hybrid molecules with significant binding affinity for μ-opioid receptors and I2-imidazoline binding sites

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 491-493

2002

  1. Guanidinium and aminoimidazolinium derivatives of N-(4-piperidyl)propanamides as potential ligands for μ opioid and I2-imidazoline receptors: Synthesis and pharmacological screening

    Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 4, pp. 1009-1018

  2. I2-imidazoline binding site affinity of a structurally different type of ligands

    Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 5, pp. 1525-1533

  3. Long-acting fentanyl analogues: Synthesis and pharmacology of N-(1-Phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides

    Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 3, pp. 817-827

  4. Synthesis and opioid activity of new fentanyl analogs

    Life Sciences, Vol. 71, Núm. 9, pp. 1023-1034