Determinación de factores premórbidos y pronósticos en pacientes con un primer episodio psicótico tratados con risperidona
- R. Segarra
- M. Gutiérrez 1
- A. González-Pinto 2
- 1 Hospital de Cruces. Barakaldo
- 2 Hospital Santiago Apostol. Vitoria.
ISSN: 1134-5934
Datum der Publikation: 2002
Ausgabe: 9
Nummer: 4
Seiten: 143-153
Art: Artikel
Andere Publikationen in: Psiquiatría biológica: Publicación oficial de la Sociedad Española de Psiquiatría Biológica
Zusammenfassung
Given that there is no standard form of treatment of psychosis, we believe it is essential to consider certain factors (premorbid adjustment, obstetric complications and cognitive dysfunction, as well as clinical sociodemographic and psychopathological parameters) as possible clinical predictors of treatment response. We carried aut an observational, multicenter, open, prospective study with a 2-year follow-up in 436 patients to evaluate acute response to early oral risperidone treatment. Factors predictive of a favorable response to risperidone treatment were pharmacologic treatment in the early phase of psychotic symptoms, acute onset of the illness, better premorbid adjustment and a better response in the WAIS information test.