Vasculitis necrotizantes sistémicas, vasculitis asociadas a ANCA
ISSN: 0304-5412
Datum der Publikation: 2013
Titel der Ausgabe: Enfermedades del sistema inmune (VI): vasculitis y miopatías inflamatorias
Serie: 11
Nummer: 33
Seiten: 2021-2028
Art: Artikel
Andere Publikationen in: Medicine: Programa de Formación Médica Continuada Acreditado
Ziele für nachhaltige Entwicklung
Zusammenfassung
Systemic necrotizing vasculitides are a non homogeneous group of diseases defined by clinical symptoms of multivisceral involvement that are the consequence of severe inflammation of the arterial wall and histologically for the presence of fibrinoid necrosis. The polyarteritis nodosa (PAN) is a systemic vasculitides that affect the small-and medium-sized arteries. Antineutrophil cytoplasmatic antibody (ANCAs)-associated vasculitides include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and the allergic granulomatosis and angiitis or Churg Strauss syndrome (CSS) that affect essentially small-sized arteries. GPA and MPA vasculitides have a common renal involvement (pauci-immune crescentic glomerulonephritis) and share treatment and evolution. The SCS has a different presentation and prognosis compared with the other ANCAs.