Application of genomic surveillance in Cantabria to keep the COVID-19 pandemic under control

  1. Curiel-del-Olmo, Soraya 14
  2. Rodríguez-Lozano, Jesús 2
  3. Aginagalde, Adrián-Hugo 3
  4. Barquín, Gloria 4
  5. Pardo, Jaime 4
  6. Damián, Elena 4
  7. Velasco, Silvia 2
  8. Gozalo, Mónica 2
  9. Iglesias-Caballero, María 5
  10. López-González, María 4
  11. Freije, Ana 4
  12. López-Gómez, Tania 4
  13. Calvo-Montes, Jorge 2
  14. Wallmann, Reinhard 4
  1. 1 Servicio Cántabro de Salud. Hospital Universitario Marqués de Valdecilla (HUMV). Unidad de Genética. Santander, España
  2. 2 Hospital Universitario Marqués de Valdecilla
    info

    Hospital Universitario Marqués de Valdecilla

    Santander, España

    ROR https://ror.org/01w4yqf75

  3. 3 Servicio Cántabro de Salud. Fundación Marqués de Valdecilla. Observatorio de Salud Pública de Cantabria. Santander, España
  4. 4 Gobierno de Cantabria
    info

    Gobierno de Cantabria

    Santander, España

  5. 5 Centro Nacional de Microbiología
    info

    Centro Nacional de Microbiología

    Majadahonda, España

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Zeitschrift:
Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios

ISSN: 0304-4858,  2173-2302

Datum der Publikation: 2022

Ausgabe: 119

Nummer: 1

Seiten: 27-37

Art: Artikel

DIALNET GOOGLE SCHOLAR lock_openOpen Access editor

Andere Publikationen in: Gaceta médica de Bilbao: Revista oficial de la Academia de Ciencias Médicas de Bilbao. Información para profesionales sanitarios

Zusammenfassung

A number of variants of the SARS-CoV-2 virus are now causing special concern all around the world due to its purported ability to evade the immune response in previously immunized people. Therefore, many governments, including that of Spain, have implemented non-pharmaceutical interventions (NPI) in an attempt to prevent variants of concern (VOCs) from being imported and, if they are, facilitate their timely detection and control their expansion throughout new regions.In this report, the real efficacy of the current NPI is subjected to examination, using the first COVID-19 outbreak of P.1 lineage (Gamma variant) arisen in Cantabria as a practical example. Likewise, the usefulness of genomic surveillance in keeping a pandemic situation under control is also assessed. Finally, the issue of whether there really exists in Spain, as well as in every Autonomous Community, the capacity to perform sufficiently broad genetic analyses, in a sufficiently short time and in a sufficient amount of samples, as to have real-time data on the evolution of the variants is addressed here. The COVID-19 outbreak reported in this work was kept under control and its expansion was avoided. However, analysing the facts, this success seems to be largely due to a surprisingly low transmission capacity of this strain of the virus, while not so much to a high efficiency of the existing NPI. Indeed, the attack rate of this outbreak has been as low as 3.5%.

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