Publicaciones (37) Publicaciones de SEAN ROBERT CONNELL

2023

  1. CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function

    mBio, Vol. 14, Núm. 4

  2. CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state

    Nature Microbiology, Vol. 8, Núm. 10, pp. 1834-1845

  3. Disruption of Dcp1 leads to a Dcp2-dependent aberrant ribosome profiles in Aspergillus nidulans

    Molecular Microbiology, Vol. 119, Núm. 5, pp. 630-639

2022

  1. Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods

    Frontiers in Microbiology, Vol. 13

2021

  1. A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit

    Science Advances, Vol. 7, Núm. 23

  2. Histone mRNA is subject to 3′ uridylation and re-adenylation in Aspergillus nidulans

    Molecular Microbiology, Vol. 115, Núm. 2, pp. 238-254

2020

  1. Backbone and sidechain NMR assignments for the ribosome maturation factor RbfA from Escherichia coli

    Biomolecular NMR Assignments, Vol. 14, Núm. 2, pp. 317-321

  2. Backbone and sidechain NMR assignments for the ribosome maturation factor RimP from Escherichia coli

    Biomolecular NMR Assignments, Vol. 14, Núm. 2, pp. 189-193

2017

  1. RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket

    Nucleic Acids Research, Vol. 45, Núm. 11, pp. 6945-6959

  2. Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

    Nucleic acids research, Vol. 45, Núm. 4, pp. 2179-2187

2016

  1. Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 16, pp. E2286-E2295

  2. The novel aminomethylcycline omadacycline has high specificity for the primary tetracycline-binding site on the bacterial ribosome

    Antibiotics, Vol. 5, Núm. 4

2015

  1. Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A

    Nucleic Acids Research, Vol. 43, Núm. 20, pp. 10015-10025

  2. Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome

    Antimicrobial Agents and Chemotherapy, Vol. 59, Núm. 5, pp. 2849-2854

2013

  1. Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology

    Journal of Biomolecular NMR, Vol. 56, Núm. 2, pp. 85-93

  2. Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex

    Structure, Vol. 21, Núm. 7, pp. 1251-1257

2010

  1. Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

    Nature, Vol. 468, Núm. 7324, pp. 713-716

2009

  1. GTPase activation of elongation factor EF-Tu by the ribosome during decoding

    EMBO Journal, Vol. 28, Núm. 6, pp. 755-765

2008

  1. A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

    Nature Structural and Molecular Biology, Vol. 15, Núm. 9, pp. 910-915

  2. The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Núm. 36, pp. 13339-13344