SEAN ROBERT
CONNELL
Argitalpenak (37) SEAN ROBERT CONNELL argitalpenak
2023
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CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function
mBio, Vol. 14, Núm. 4
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CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Nature Microbiology, Vol. 8, Núm. 10, pp. 1834-1845
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Disruption of Dcp1 leads to a Dcp2-dependent aberrant ribosome profiles in Aspergillus nidulans
Molecular Microbiology, Vol. 119, Núm. 5, pp. 630-639
2022
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Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods
Frontiers in Microbiology, Vol. 13
2021
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A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit
Science Advances, Vol. 7, Núm. 23
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Histone mRNA is subject to 3′ uridylation and re-adenylation in Aspergillus nidulans
Molecular Microbiology, Vol. 115, Núm. 2, pp. 238-254
2020
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Backbone and sidechain NMR assignments for the ribosome maturation factor RbfA from Escherichia coli
Biomolecular NMR Assignments, Vol. 14, Núm. 2, pp. 317-321
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Backbone and sidechain NMR assignments for the ribosome maturation factor RimP from Escherichia coli
Biomolecular NMR Assignments, Vol. 14, Núm. 2, pp. 189-193
2017
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RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket
Nucleic Acids Research, Vol. 45, Núm. 11, pp. 6945-6959
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Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways
Nucleic acids research, Vol. 45, Núm. 4, pp. 2179-2187
2016
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Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Núm. 16, pp. E2286-E2295
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The novel aminomethylcycline omadacycline has high specificity for the primary tetracycline-binding site on the bacterial ribosome
Antibiotics, Vol. 5, Núm. 4
2015
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Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A
Nucleic Acids Research, Vol. 43, Núm. 20, pp. 10015-10025
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Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome
Antimicrobial Agents and Chemotherapy, Vol. 59, Núm. 5, pp. 2849-2854
2013
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Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology
Journal of Biomolecular NMR, Vol. 56, Núm. 2, pp. 85-93
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Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
Structure, Vol. 21, Núm. 7, pp. 1251-1257
2010
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Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
Nature, Vol. 468, Núm. 7324, pp. 713-716
2009
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GTPase activation of elongation factor EF-Tu by the ribosome during decoding
EMBO Journal, Vol. 28, Núm. 6, pp. 755-765
2008
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A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nature Structural and Molecular Biology, Vol. 15, Núm. 9, pp. 910-915
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The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Núm. 36, pp. 13339-13344